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6000 species in 500 genera constitute one of the largest families of plants. Most are tropical but a number occur in temperateregions and there are a few Arctic species. Several are myrmecophilous (inhabited by ants). Randia spinosa and Vanqueria spinosa make spiny hedges. Asperula odorata provides aroma chemicals. Genera assigned to Naucleaceae (syn. Rubiaceae) (Willis 1973) are included here.
[Summary yet to be added]
- Adina cordifolia
The wood is said to be irritant to the respiratory tract (Orsler 1973).
- Asperula L.
Over 200 species are found in Europe and Asia especially in the Mediterranean region; sixteen species are found in eastern Australia and Tasmania. Species of this genus have hooked fruits which attach themselves to animals (Howes 1974).
- Bertiera racemosa
The leaves have styptic properties (Irvine 1961).
- Borreria compacta
The use of a paste of the leaf by the Ikizu as a counter-irritant in the way that a mustard leaf or plaster (Brassica) has been used by Europeans is noted by Bally (1937, 1938). There is a considerable degree of itch from the application which is followed by scaling (Bally 1938).
- Canthium coprosmoides
After grazing on this plant for three days, animals died in agony after the skin had blistered and the hair peeled off (Hurst 1942).
- Catesbaea melanocarpa
The plant is listed as a cause of mechanical injury (Oakes and Butcher 1962).
- Cephaelis ipecacuanha
The root provides medicinal ipecacuanha. The dust or effluvium of the root produces inflammation of the air-passages and conjunctivitis, and applied to the skin in the form of an ointment, it excites a pustular eruption similar to that caused by tartar emetic (Dispensatory 1884). Acute keratoconjunctivitis follows instillation of the powder into the eye. More chronic contamination may lead to the development of a granular conjunctivitis resembling trachoma. These reactions are sometimes seen in pharmacists who handle the powder either of ipecacuanha or of emetine but the most dramatic incidents have been self-inflicted by malingerers (Duke-Elder & MacFaul 1972b). The particles of ipecac have a distinctive microscopical appearance which permits their identification if malingering is suspected (Grant 1962). Dermatitis from ipecacuanha was reported by Benjamin (1903), Robert (1922), Galewsky (1926), Hirszfeldowa and Prokopowicz-Wierzbowska (1924) and Lortat-Jakob et al. (1930). Erythema, papules and intensive pruritus leading to crusted excoriations followed topical exposure to the drug (Bazin cited by White 1887). Vesicular and pustular reactions have been observed following local application of the crude drug to healthy skin (Piffard 1881, White 1887).
Emetine, the principal alkaloid of ipecacuanha, produced redness, papules, vesicles, pustules and urticaria on the forearms and arms of pharmacists (Peshkin 1924). A chemist, a boiler and a sorter developed eczematous dermatitis from contact with emetine, while making a preparation of ipecac (Schwartz et al. 1957).
40 species are found as trees in the Andes. Several species are cultivated for their bark which yields quinine and related alkaloids.
Stripping of cinchona bark and handling of the powdered bark and quinine produced dermatitis in pharmaceutical workers. The eyelids, face, neck, elbow flexures, genital area and upper thighs were principally affected (Chevallier 1852, Dold 1925, Blamoutier and Joannon 1922). Touton (1932) and Prosser White (1934) provide an extensive bibliography. Quinine can cause allergic contact dermatitis in factory workers (White 1887, Werz 1949) and when used in dandruff cream (Johnson 1935), hair tonic (Kissmeyer 1937, Peterkin 1953), aftershave lotion (Burgess and Usher 1930) and contraceptive pessaries (Danbolt 1931, Peterkin 1953, Zheltakov and Somov 1963, Guriev and Monakhova 1968). Ingestion of quinine, as in tonic water can produce a focal flare of dermatitis (Kissmeyer 1937, Sulzberger and Baer 1948). Cross-sensitivity to related alkaloids has been observed and appears to be dependent on a quinoline ring (Bloch 1924, Ford 1934, Dawson and Garbade 1930). Contact dermatitis from the isomer, quinidine (Frenstrom 1965), and from the synthetic antimalarial, chloroquin (Hermann and Schulz 1965) is rare. Immediate hypersensitivity was reported by Gray (1929). Quinine sulfate, 2% aqueous, is suitable for patch testing (Calnan and Caron 1961). In Denmark, the incidence of sensitivity to quinine steadily declined from 1938 to 1961 and at the latter date was distinctly rare (Hjorth, personal communication to Calnan and Caron 1961).
40 species are found in palaeotropical regions especially in Africa. Several species are cultivated for their seeds, coffee beans.
- Coffea arabica
- Arabian Coffee
Workers employed in sorting milling or roasting coffee beans developed dermatitis, urticaria, rhinitis and asthma. Patch tests to the chaff produced positive results (Chopra et al. 1949, Layton et al. 1966). A role of chlorogenic acid in the respiratory symptoms suggested by Freedman et al. (1962) was discounted by Layton et al. (1966). Employees in a coffee-roasting plant developed allergic manifestations from castor-bean dust (Ricinus communis, fam. Euphorbiaceae) which contaminated the burlap bags in which the coffee was transported (Figley and Rawling 1950). Cheilitis was attributed to coffee drinking; liquid coffee produced a positive patch test reaction but controls were not recorded (Lupton 1953). None of 691 persons patch tested to an ether extract of coffee showed positive reactions (Fregert and Hjorth 1969).
Inhalation of coffee bean dust can produce coffee worker's lung, a form of allergic alveolitis (Morgan and Seaton 1975).
- Coryanthe pachyceras
- (syn. Coryanthe paniculata)
The bitter, astringent bark has a local anaesthetic action from alkaloids related to yohimbine (Dalziel 1937, Irvine 1961).
- Craterispermum laurinum
The powdered root or bark is used as a rubefacient in Central Africa (Watt & Breyer-Brandwijk 1962).
- Cuviera DC.
The genus comprises about 20 species found in tropical Africa (Mabberley 1997). Irvine (1961) lists the following species as being spiny:
- Cuviera acutiflora DC.
- Cuviera macroura Schumann
- Cuviera subuliflora Benth.
Hepper (1963) cautions that plant collectors should beware of the small biting ants that infest many Cuviera species, including Cuviera longiflora Hiern. Irvine (1961) notes that the nodes of Cuviera subuliflora Benth. harbour ants.
- Diodia teres
An extract of this plant produced a positive patch test reaction in one of 50 patients who had "weed dermatitis" (Shelmire 1939).
- Duroia hirsuta
The bark, when tied on the arm, causes blisters to form (von Reis Altschul 1973). The swollen stem of the plant regularly houses ants (Willis 1973).
- (syn. Exostemma)
50 species are found from Mexico to Brazil, Peru and the West Indies. Febrifugal alkaloids are contained in the bark.
- Exostemma caribaeum
The wood yields exostemin, a 4-phenylcoumarin related to coumarins of Dalbergia spp. (Seshadri 1972).
- Galium L.
400 species are of cosmopolitan distribution.
Species of this genus have hooked fruits which attach themselves to animals (Howes 1974).
- Galium sparine
Dermatitis was reported from contact with the stem of this plant; a patch test produced a positive result (Fujita 1966). Small reflexed hooks are present on the stem.
- Galium triflorum
- Sweet-Scented Bedstraw
For chest pains, this plant was rubbed on the skin, sometimes enough to draw blood, and then hellebore (Veratrum viride) was applied. North American Indians rub the body with the plant for its perfume, mash it and put it in the hair (Gunther 1945).
- Galium verum L.
- Lady's Bedstraw, Yellow Bedstraw, Maid's Hair, Cheese Rennet, Gailion, Pettimugget, Wild Rosemary
Stuart (1979) asserts that the dried plant is styptic and and may be applied externally to wounds and some skin eruptions.
250 species are found in palaeotropical regions.
The fruits are used for haemostasis, apparently by ingestion, and for dyeing. The flowers are used to flavour tea which is then known as jasmine tea (Smith 1969, Kariyone 1971).
The odour of gardenia can cause hayfever (Biederman 1937).
- Hydnophytum Jack
Sixty species are found in Indo-Malaysia, and especially in New Guinea. They are epiphytes, a number of which possess ant-inhabited swollen stems (Mabberley 1987). Merrill (1945) notes that the basal parts of these plants are sometimes armed with short spines.
- Hydnophytum formicarium
Menninger (1967) provides a photograph of this "ant plant" clinging to a tree.
- Mitragyna ledermannii Ridsd.
- (syn. Mitragyna ciliata Aubr. & Pellegr.)
- Mitragyna stipulosa O. Kuntze
The partially seasoned wood has a pungent smell and some workers find the sawdust to be irritating (Titmuss 1965). A silica content of up to 0.24 % has been reported for M. ciliata (Kukachka 1970). There are occasional trade complaints of dermatitis and nasal irritation in England (Orsler 1973) and in Nigeria (Woods and Calnan 1976). Wilkinson (1973) observed a case of dermatitis from the wood; a patch test produced a positive reaction. Wagenfuhr (1961) noted that the sawdust was said to cause mucosal irritation and vomiting in Germany.
Alkaloids are found in the wood of some species (Hausen 1970).
- Myrmecodia Jack
Forty five species are found from Malaysia to Fiji. They are epiphytes with swollen stems ("tubers") penetrated by numerous interconnecting galleries and inhabited by ants (Mabberley 1987).
- Nauclea diderrichii Merr.
- (syns Nauclea trillesii Merr., Sarcocephalus badi Aubrév., Sarcocephalus diderrichii De Wild., Sarcocephalus trillesii Pierre ex De Wild.)
- Bilinga, Opepe, Badi, Kusia, West African Boxwood
Harvey Gibson (1906) investigated illness amongst workmen handling "West African boxwood" during the manufacture of shuttles in Lancashire, England. Patients exhibited a pale yellowish or greenish colour of the face and body, running of the nose and eyes, chronic sneezing, headache, nausea, faintness, and breathing difficulties accompanied by a peculiar 'camphor' or 'Turkey rhubarb' odour of the breath and skin. He identified the botanical source of the wood as Sarcocephalus diderrichii De Wild., distinguishing it from East London (or South African) boxwood derived from Gonioma kamassi E.Mey., and from West Indian boxwood reputed to be derived from Tabebuia pentaphylla Hemsl. Harvey Gibson's investigation was subsequently referred to by Remington et al. (1918), by Prosser White (1934), and by others who failed to discover the erratum (Harvey-Gibson 1912) he published six years later. In this erratum, he admitted that the piece of wood provided to him as West African boxwood was in fact East London or Knysna boxwood imported from South Africa, which botanically proved to be Gonioma kamassi E.Mey. (fam. Apocynaceae) when compared with an authentic sample of this wood.
Woods & Calnan (1976) recorded that woodworkers at three factories in Ibadan, Nigeria reported that opepe irritated their skin producing craw-craw (dermatitis) in some men. Nasal irritation sometimes accompanied by fever and headache also occurred. The botanical identity of the wood was not established.
- Nauclea subdita
- Bur Flower Bush, Bengkal, Gedembah, Kedembai
The root bark yields an intensely yellow dye (Corner 1952).
- Paederia foetida
The plant has an offensive odour when bruised or even if slightly disturbed (Pope 1968) and the foul-smelling stems and leaves are used to stimulate moribund persons (Smith 1969).
- Pausinystalia johimbe Beille
- (syns Coryanthe johimbe Schumann)
This plant yields yohimbine, an adrenergic blocking agent which has been used for its alleged aphrodisiac properties (Reynolds 1996). Four of 6 impotent diabetics with paraesthesia of the lower limbs, noted prompt relief after taking yohimbine 6mg thrice daily by mouth. The paraesthesia recurred when treatment was interrupted (Morales et al. 1981).
- Pentanisia prunelloides Walp.
- (syns Declieuxia prunelloides Klotzsch ex Eckl. & Zeyh., Diotocarpus prunelloides Hochst.)
- Wild Verbena
[Information available but not yet included in database]
- Rothmannia longiflora
The fruits yield a black dye which is used in Nigeria for making blue-black markings on the face or body (Oliver 1961).
60 species are found in western and central Europe, the Mediterranean region, eastern tropical and southern Africa, temperate Asia, the Himalayas and from Mexico to tropical South America. Several species yield dyes.
- Rubia tinctorum
The plant was formerly cultivated for its root which yields the dye alizarin. Alizarin is a sensitiser (Greenberg and Lester 1954) and on that account has been removed from certain brand-name cosmetics (Anon 1973).
- Sarcocephalus latifolius E.A.Bruce
- (syns Cephalina esculenta Schumach. & Thonn., Nauclea esculenta Merr., Nauclea latifolia Sm., Sarcocephalus esculentus Afzel. ex Sabine, Sarcocephalus russeggeri Kotschy ex Schweinf., Sarcocephalus sambucinus K.Schum.)
- African Peach, Country Fig, Guinea Peach, Strawberry Tree, Pêcher Africain, Liane à Fraise
[Information available but not yet included in database]
- Spermacoce chaetocephala DC. var chaetocephala
- (syns Borreria chaetocephala Hepper, Borreria compacta K.Schum., Borreria kotschyana K.Schum., Spermacoce compacta Hochst. ex Hiern, Spermacoce kotschyana Oliv.)
In East Africa, the leaf of Spermacoce compacta is used as a rubefacient and for the treatment of skin rashes (Githens 1949, Watt & Breyer-Brandwijk 1962).
- Uncaria gambir Roxb.
- (syns Nauclea gambir Hunter, Ourouparia gambir Baill.)
The dried aqueous extract of the leaves and young twigs of this climbing shrub provides a medicinal product known as pale catechu, otherwise known as catechu pallidum, gambier, or gambir. Tanners refer to this as terra japonica. A similar material may also be derived from Uncaria acida Roxb. Pale catechu has properties and uses similar to those of black catechu derived from Acacia catechu Willd., fam. Leguminosae (Pereira 1842, Felter & Lloyd 1898, Trease & Evans 1966).
- Anon (1973) Almay Hypo-Allergenic Cosmetics Product Formulary, 8th edn: Schieffelin and Co., Pharmaceutical Laboratories Division, 562-5th Ave., New York, N.Y. 10036
- Bally (1937, 1938) cited by Watt, J.M. and Breyer-Brandwijk, M.G. (1962)
- Bazin cited by White (1887).
- Benjamin (1903) Schmidts Jb 278: 133. Cited by Touton (1932).
- Biederman, J.B. (1937) Sensitivity to flowers. Larynogoscope 47: 825.
- Blamoutier and Joannon (1922) Quinine sickness of occupational origin. Rev. d'Hyg. 44: 521. Cited by Prosser White (1934).
- Bloch, B. (1924) Arch. Derm. Syph. (Berl.). Cited by Calnan and Caron (1961).
- Budavari S (Ed.) (1996) The Merck Index. An Encyclopedia of Chemicals, Drugs, and Biologicals. 12th edn. Whitehouse Station, NJ: Merck & Co., Inc.
- Burgess, J.F. and Usher, B. (1930) On hypersensitiveness to quinine. Canad. Med. Ass. J. 23: 45.
- Calnan, C.D. and Caron, G.A. (1961) Quinine sensitivity. Br. Med. J. 2: 1750.
- Chevalier, A. (1852) Essay upon the health of workers who prepare sulphate of quinine. Ann. d'Hygiene 48: 95. Cited by Prosser White (1934).
- Chopra, R.N., Badhwar, R.L. and Ghosh, S. (1948) Poisonous Plants of India. Monograph No. 17. Delhi. Indian Council of Agricult. Res.
- Corner EJH (1952) Wayside Trees of Malaya, 2nd edn. Vol. 1. Singapore: VCG Gatrell, Government Printer.
- Dalziel JM (1937) The Useful Plants of West Tropical Africa. Being an appendix to The Flora of West Tropical Africa by J. Hutchinson and J.M. Dalziel. London: Crown Agents for the Colonies [WorldCat]
- Danbolt, N. (1931) Eczema due to suppositories in persons hypersensitive to quinine. Norsk. Mag. f. Laegervidensk. 92: 623.
- Dawson, W.T. and Garbade, F.A. (1930) Idiosyncrasy to quinine, cinchonidene and ethylhydrocupreine. J. Am. Med. Ass. 94: 704.
- Dispensatory (United States) (1884). Cited by White (1887).
- Dispensatory of the USA. (1926) 21st edn. Philadelphia. J.B. Lippincott Co. pp. 600-601. Cited by Siegel (1954).
- Dold, H. (1925) Quinine idiosyncrasy of the skin in industrial workers. Arch. f. Hyg. 96: 167. Cited by Prosser White (1934).
- Duchworth, personal communication to White (1887).
- Duke-Elder S, MacFaul PA (1972b) System of Ophthalmology, Vol. XIV. Injuries Part 2. Non-Mechanical Injuries. London: Henry Kimpton [WorldCat]
- Felter HW, Lloyd JU (1898) King's American Dispensatory, 18th edn; 3rd revn, I & II. Cincinnati: Ohio Valley [WorldCat] [url]
- Fernstrom, A.I.B. (1965) Occupational quinidine contact dermatitis. Acta Derm.-Vener. 45: 129.
- Figley, K.D. and Rawling, F.A.A. (1950) Castor bean: industrial hazard as contaminant of green coffee dust and used burlap bags. J. Allergy 21: 545.
- Ford, W.K. (1934) Drug eruption due to quinine: recurrence following use of contraceptive. J. Am. Med. Ass. 103: 483.
- Freedman, S.O. et al. (1962) Identification of a simple chemical compound (chlorogenic acid) as an allergen in plant materials causing human atopic disease. Am. J. Med. Sci. 244: 548.
- Fregert S and Hjorth N (1969) Results of standard patch tests with substances abandoned. Contact Dermatitis Newsletter (5): 85
- Fujita, E. (1966) Jap. J. Derm. 76: 703. Cited by Ito (1972).
- Galewsky (1926) Uber die gewerbliche Schadigung durch Emetin. Wien. Med. Wschr. 76: 17, 10 July. Cited by Touton (1932).
- Githens TS (1949) Drug Plants of Africa (African Handbooks, No. 8). Philadelphia: University of Pennsylvania Press [WorldCat] [url]
- Grant, W.M. (1962) Toxicology of the Eye. Springfield, Ill. Charles C. Thomas.
- Gray St., G.B.D. (1929) Idiosyncrasy to quinine injections. Br. Med. J. 1: 200.
- Greenberg, L.A. and Lester, D. (1954) Handbook of Cosmetic Materials. New York. Interscience.
- Gunther, E. (1945) Ethnobotany of Western Washington. Seattle. University of Washington Press.
- Guriev, L.N. and Monakhova, A.P. (1968) Contact-allergic dermatitis of sexual organs in men due to quinine. Vest. Derm. Vener. 42: 87.
- Harvey Gibson RJ (1906) The physiological properties of 'West African boxwood'. Biochemical Journal 1(1): 39-53
- Harvey-Gibson RJ (1912) Note on the synonymy and histological characters of East London boxwood (Gonioma kamassi, E. Mey.). Biochemical Journal 6(1): 127-129
- Hausen, B.M. (1970) Untersuchungen uber Gesundheitsschadigende Holzer. Thesis, Hamburg.
- Hermann, W.P. and Schulz, K.H. (1965) Allergic contact eczema from resochin. Dermatologica 130: 216.
- Hepper FN (1963) Plants of the 1957-58 West African Expedition. III. Kew Bulletin 16(3): 451-459
- Hirszfeldowa and Prokopowicz-Wierzboska (1924) Uber das Wesen der Idiosynkrasie bei Kindern. Pedjatr. Polska 4: 360. Cited by Touton (1932).
- Hjorth, N. Personal communication to Calnan, C.D. and Caron, G.A. (1961).
- Howes FN (1974) A Dictionary of Useful and Everyday Plants and their Common Names. Cambridge: Cambridge University Press [WorldCat]
- Hurst E (1942) The Poison Plants of New South Wales. Sydney: NSW Poison Plants Committee [WorldCat]
- Irvine FR (1961) Woody Plants of Ghana. With special reference to their uses. London: Oxford University Press [doi] [WorldCat] [url] [url-2]
- Ito, K. (1972) Personal communication to JC Mitchell.
- Johnson, D.W. (1935) Dermatitis due to application of dandruff cream. Urol. Cutan. Rev. 39: 173.
- Kakachka, B.F. (1970) Properties of imported tropical woods. USDA Forest Service Research Paper. FPL125 March. U.S. Dept. Agric. Forest Service. Forest Products Laboratory. Madison, Wis. USA
- Kaplan, R.J., Daman, L., Shereff, R. Rosenberg, E.W. and Robinson, H. (1976) Letter: treatment of atopic dermatitis with topically applied caffeine. Arch. Dermatol. 112: 880 and letter 113: 107.
- Kariyone, T. (1971) Atlas of Medicinal Plants. Osaka, Japan. Takeda Chemical Industries.
- Kissmeyer, A. (1937) Trois cas d'intolerance a la quinine. Abstr. Acta Derm.-Venereol. 19: 153.
- Layton, L.D., Panzani, R. and Corse, J.W. (1966) Non-diffusable allergenic contaminant from samples of chlorogenic acid causing allergic reaction: Pure chlorogenic acid not an allergen. J. Allergy 38: 268 and correspondence p. 276.
- Levantine, A. and Almeyda, J. (1974) Cutaneous reactions to food and drug additives. Brit. J. Derm. 91: 359.
- Lortat-Jakob, Flandrin and Poumeau-Delille (1930) Un cas d'anaphylaxie cutanee a l'emetine. Bull. Soc. Franc. Derm. Syph. 36: 1088. Cited by Touton (1932).
- Lupton, E.S. (1953) Cheilitis due to coffee. Archs Derm. Syph. 68: 333.
- Mabberley DJ (1987) The Plant-Book. A portable dictionary of the higher plants. Cambridge: Cambridge University Press
- Menninger EA (1967) Fantastic Trees. New York: Viking Press [WorldCat]
- Merrill ED (1945) Plant Life of the Pacific World. New York: Macmillan. Cited by Menninger (1967)
- Morales A et al. (1981) New England Journal of Medicine 305: 1221.
- Morgan, W.K.C. and Seaton, A. (1975) Occupational Lung Diseases. Philadelphia, Saunders.
- Oakes AJ, Butcher JO (1962) Poisonous and Injurious Plants of the U.S. Virgin Islands. Miscellaneous Publication No. 882. Washington, DC: Agricultural Research Service, United States Department of Agriculture [WorldCat]
- Oliver, B. (1961) Nigeria's Useful Plants. Nigerian Field, Part V. 26: 170-180.
- Orsler, R.J. (1973) Personal communication to JC Mitchell from Forest Products Research Laboratory, Princes Risborough, Bucks, England.
- Pereira J (1842) Elements of Materia Medica and Therapeutics, 2nd edn, Vols 1 & 2. London: Longman, Brown, Green, and Longmans [WorldCat]
- Peshkin, M.M. (1924) Bronchial asthma and other allergic manifestations in pharmacists. J. Am. Med. Ass. 82: 1854.
- Peterkin,.G.A.G. (1953) Drug eruptions in the tropics. In: Handbook of Tropical Dermatology and Medical Mycology. ed Simons, R.D.G. Ph. Amsterdam. Elsevier. pp. 1453.
- Piffard HG (1881) A Treatise on the Materia Medica and Therapeutics of the Skin. New York: William Wood & Company [WorldCat] [url] [url-2]
- Pope, W.T. (1968) Manual of Wayside Plants of Hawaii. Rutland, Vermont. Charles E. Tuttle Co.
- Prosser White R (1934) The Dermatergoses or Occupational Affections of the Skin, 4th edn. London: HK Lewis [doi] [WorldCat] [url] [url-2]
- Remington JP, Wood HC, Sadtler SP, LaWall CH, Kraemer H, Anderson JF (Eds) (1918) The Dispensatory of the United States of America. 20th edn. Philadelphia: JB Lippincott [WorldCat] [url] [url-2]
- Reynolds JEF (Ed.) (1996) Martindale. The Extra Pharmacopoeia. 31st edn. London: Royal Pharmaceutical Society [WorldCat]
- Robert (1922) Un cas d'anaphylaxie locale a l'emetine. Bull. Soc. Path. Exot. Paris 15: 680. Cited by Touton (1932).
- Schwartz, L., Tulipan, L., and Birmingham, D.J. (1957) Occupational Diseases of the Skin. 3rd edn. Philadelphia. Lea and Febiger.
- Seshadri, T.R. (1972) Polyphenols of Pterocarpus and Dalbergia woods. Phytochemistry 11: 881.
- Shelmire, B. (1939) Contact dermatitis from weeds: Patch testing with their oleoresins. J. Am. Med. Ass. 113: 1085 (and unpublished table accompanying reprints, courtesy of Dr David Shelmire).
- Siegel, J.M. (1954) Dermatitis due to black walnut juice. Archs Derm. Syph. 70: 511.
- Smith, F.P. (1969) Chinese Materia Medica. Vegetable kingdom. 2nd edn. Rev. by Hei, P.D. Taipei, Taiwan. Ku T'ing Book House.
- Stuart M (1979) Reference section. In: Stuart M (Ed.) The Encyclopedia of Herbs and Herbalism, pp. 141-283. London: Orbis Publishing [WorldCat]
- Sulzberger, M.B. and Baer, R.L. (1948) Eczematous eruptions of the hands. In: Year Book of Dermatology. Chicago. Year Book Publishers.
- Touton K (1932) Hauterkrankungen durch phanerogamische Pflanzen und ihre Produkte (Toxicodermia et Allergodermia phytogenes) [Skin Diseases Caused by Phanerogamic Plants and their Products (Toxicodermia et Allergodermia phytogenes)]. In: Jadassohn J (Ed.) Handbuch der Haut- und Geschlechtskrankheiten. Band IV, Teil I. Angeborene Anomalien. Lichtdermatosen. Pflanzengifte. Thermische Schädigungen. Einfluss Innerer Störungen auf die Haut [Handbook of Skin and Venereal Diseases. Volume IV, Part I. Congenital abnormalities. Photodermatoses. Plant toxins. Thermal injuries. Influence of internal disorders on the skin], pp. 487-697. Berlin: Julius Springer [doi] [WorldCat] [url] [url-2]
- Trease GE, Evans WC (1966) A Textbook of Pharmacognosy, 9th edn. London: Baillière, Tindall and Cassell [WorldCat]
- von Reis Altschul S (1973) Drugs and Foods from Little-Known Plants. Notes in Harvard University Herbaria. Cambridge, MA: Harvard University Press [WorldCat] [doi] [url] [url-2]
- Watt JM, Breyer-Brandwijk MG (1962) The Medicinal and Poisonous Plants of Southern and Eastern Africa. Being an account of their medicinal and other uses, chemical composition, pharmacological effects and toxicology in man and animal, 2nd edn. Edinburgh: E & S Livingstone [doi] [WorldCat] [url] [url-2]
- Werz, J.F.C. (1949) Contact dermatitis in workers in quinine plant. Ned. T. Geneesk 93: 170.
- White JC (1887) Dermatitis Venenata: an account of the action of external irritants upon the skin. Boston: Cupples and Hurd [doi] [WorldCat] [url] [url-2]
- Wilkinson, D.S. (1973) Personal communication to JC Mitchell.
- Willis JC (1973) A Dictionary of the Flowering Plants and Ferns, 8th edn. (Revised by Airy Shaw HK). Cambridge: Cambridge University Press [WorldCat]
- Wagenfuhr, R. (1961) Gift es giftige Holzer. Mobel and Wohnraum 4: 120.
- Woods B, Calnan CD (1976) Toxic woods. British Journal of Dermatology 95(Suppl 13): 1-97 [doi] [url] [url-2] [pmid]
- Zheltakov, M.M. and Somov, B.A. (1963) Allergic quinine dermatitis caused by contraceptives. Vest. Derm. Vener. 12: 8.